Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing

We used deep sequencing technology to profile the transcriptome, gene copy number, and CpG island methylation status simultaneously in eight commonly used breast cell lines to develop a model for how these genomic features are integrated in estrogen receptor positive (ER+) and negative breast cancer...

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Veröffentlicht in:PloS one 2011-02, Vol.6 (2), p.e17490-e17490
Hauptverfasser: Sun, Zhifu, Asmann, Yan W, Kalari, Krishna R, Bot, Brian, Eckel-Passow, Jeanette E, Baker, Tiffany R, Carr, Jennifer M, Khrebtukova, Irina, Luo, Shujun, Zhang, Lu, Schroth, Gary P, Perez, Edith A, Thompson, E Aubrey
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Sprache:eng
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