Steroid concentrations in plasma, whole blood and brain: effects of saline perfusion to remove blood contamination from brain

The brain and other organs locally synthesize steroids. Local synthesis is suggested when steroid levels are higher in tissue than in the circulation. However, measurement of both circulating and tissue steroid levels are subject to methodological considerations. For example, plasma samples are comm...

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Veröffentlicht in:	PloS one 2010-12, Vol.5 (12), p.e15727
Hauptverfasser:	Taves, Matthew D, Schmidt, Kim L, Ruhr, Ilan M, Kapusta, Katarzyna, Prior, Nora H, Soma, Kiran K
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Analysis Animals Biology Blood Blood cells Blood circulation Blood-brain barrier Brain Brain - metabolism Brain - pathology Brain research Contamination Corticosterone Corticosterone - blood Dehydroepiandrosterone Dehydroepiandrosterone - blood Diencephalon Erythrocytes Erythrocytes - metabolism Estrogens Estrogens - blood Finches Ischemia Male Metabolism Models, Biological Neurosciences Organs Perfusion Plasma Radioimmunoassay Regulation Sex hormones Sodium Chloride - metabolism Steroid hormones Steroids Steroids - metabolism Studies Taeniopygia guttata Telencephalon Testosterone Testosterone - blood Tissue Distribution Zebra finch Zoology
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