RNA polymerase II binding patterns reveal genomic regions involved in microRNA gene regulation

MicroRNAs are small non-coding RNAs involved in post-transcriptional regulation of gene expression. Due to the poor annotation of primary microRNA (pri-microRNA) transcripts, the precise location of promoter regions driving expression of many microRNA genes is enigmatic. This deficiency hinders our...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2010-11, Vol.5 (11), p.e13798-e13798
Hauptverfasser:	Wang, Guohua, Wang, Yadong, Shen, Changyu, Huang, Yi-wen, Huang, Kun, Huang, Tim H M, Nephew, Kenneth P, Li, Lang, Liu, Yunlong
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis Annotations Binding Binding sites Bioinformatics Biology Biosynthesis Breast cancer Cancer Cell cycle Cell Line, Tumor Chromatin Immunoprecipitation Computational Biology Computational Biology - methods Computational Biology/Genomics Computational Biology/Systems Biology Computational Biology/Transcriptional Regulation Computer applications Computer science Conservation Conserved sequence CpG islands CpG Islands - genetics Deoxyribonucleic acid DNA DNA-directed RNA polymerase Gene expression Gene Expression Regulation Gene regulation Genes Genetic aspects Genomes Genomics Histones - metabolism Humans Immunology Lysine - metabolism Mathematical models Medicine Methylation MicroRNA MicroRNAs MicroRNAs - genetics miRNA Post-transcription Promoter Regions, Genetic - genetics Protein Binding Proteins Regulatory Sequences, Nucleic Acid - genetics Ribonucleic acid RNA RNA polymerase II RNA Polymerase II - metabolism Spatial distribution Statistical models Steroid hormones Tamoxifen Transcription (Genetics) Transcription factors Transcription initiation Transcription Initiation Site Transcription, Genetic Trends Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!