Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects

To explore the potential of deep HIV-1 sequencing for adding clinically relevant information relative to viral population sequencing in heavily pre-treated HIV-1-infected subjects. In a proof-of-concept study, deep sequencing was compared to population sequencing in HIV-1-infected individuals with p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2011-05, Vol.6 (5), p.e19461-e19461
Hauptverfasser:	Codoñer, Francisco M, Pou, Christian, Thielen, Alexander, García, Federico, Delgado, Rafael, Dalmau, David, Álvarez-Tejado, Miguel, Ruiz, Lidia, Clotet, Bonaventura, Paredes, Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Added value AIDS Algorithms Anti-HIV Agents - pharmacology Anti-Retroviral Agents - pharmacology Antiretroviral agents Antiretroviral drugs Antiviral agents Darunavir DNA polymerases Drug development Drug resistance Drug Resistance, Viral - genetics Efavirenz Failure Female Genotype Genotypes High-Throughput Nucleotide Sequencing - methods HIV HIV Infections - drug therapy HIV-1 Human immunodeficiency virus Humans Indinavir Male Medicine Mutation Nucleoside reverse transcriptase inhibitors Patient compliance Predictions Protease inhibitors Pyridines - pharmacology Pyrones - pharmacology Pyrrolidinones - pharmacology Raltegravir Potassium RNA-directed DNA polymerase Salvage Salvage Therapy Sulfonamides - pharmacology Therapy Treatment Failure
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!