Variation in LPA is associated with Lp(a) levels in three populations from the Third National Health and Nutrition Examination Survey

The distribution of lipoprotein(a) [Lp(a)] levels can differ dramatically across diverse racial/ethnic populations. The extent to which genetic variation in LPA can explain these differences is not fully understood. To explore this, 19 LPA tagSNPs were genotyped in 7,159 participants from the Third...

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Veröffentlicht in:	PloS one 2011-01, Vol.6 (1), p.e16604
Hauptverfasser:	Dumitrescu, Logan, Glenn, Kimberly, Brown-Gentry, Kristin, Shephard, Cynthia, Wong, Michelle, Rieder, Mark J, Smith, Joshua D, Nickerson, Deborah A, Crawford, Dana C
Format:	Artikel
Sprache:	eng
Schlagworte:	African Americans Apolipoproteins Biology Biophysics Black People - genetics Cardiovascular disease Deoxyribonucleic acid Disease control DNA Genetic diversity Genetic research Genetic Variation Genetics Genomes Genomics Genotype Genotype & phenotype Health surveys Hispanic Americans Hispanic or Latino - genetics Humans Lipoprotein A Lipoprotein(a) - blood Lipoprotein(a) - genetics Lipoproteins Medicine Minority & ethnic groups Nutrition Physiology Polymorphism Polymorphism, Single Nucleotide Population Population Groups - genetics Populations Procedure manuals Single-nucleotide polymorphism Social and Behavioral Sciences Studies Subpopulations Surveys White People - genetics
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