Serum S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients

Ovarian cancer is the 5th leading cause of cancer related deaths in women. Five-year survival rates for early stage disease are greater than 94%, however most women are diagnosed in advanced stage with 5 year survival less than 28%. Improved means for early detection and reliable patient monitoring...

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Veröffentlicht in:	PloS one 2009-10, Vol.4 (10), p.e7670-e7670
Hauptverfasser:	Wei, Bih-Rong, Hoover, Shelley B, Ross, Mark M, Zhou, Weidong, Meani, Francesco, Edwards, Jennifer B, Spehalski, Elizabeth I, Risinger, John I, Alvord, W Gregory, Quiñones, Octavio A, Belluco, Claudio, Martella, Luca, Campagnutta, Elio, Ravaggi, Antonella, Dai, Ren-Ming, Goldsmith, Paul K, Woolard, Kevin D, Pecorelli, Sergio, Liotta, Lance A, Petricoin, Emanuel F, Simpson, R Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Animal models Animal tissues Animals Antigens Bioassays Biological assays Biology Biomarkers Biomarkers, Tumor Cancer Cancer research Cell Cycle Proteins - blood Cell Line, Tumor Chromatography Correlation analysis Data processing Disease Progression Drug dosages Female Gastric cancer Gene Expression Regulation, Neoplastic Genetics Humans Immunoassay Laboratories Liquid chromatography Liver cancer Longitudinal studies Low molecular weights Mass spectrometry Mass Spectrometry - methods Mass spectroscopy Mathematical models Medical research Medicine Metastasis Mice Mice, Nude Middle Aged Molecular weight Monitoring Neoplasm Metastasis Neoplasm Transplantation Oncology/Gynecological Cancers Ovarian cancer Ovarian carcinoma Ovarian Neoplasms - blood Ovarian Neoplasms - genetics Pathology Pathology/Molecular Pathology Peptides Peritoneum Physiology Proteins Proteomics Proteomics - methods Regression analysis S100 Calcium Binding Protein A6 S100 Proteins - blood Spectroscopy Survival Tumor cells Tumors Women's Health/Gynecological Cancers Xenografts
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