Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs

Cell-derived microvesicles (MVs) have been described as a new mechanism of cell-to-cell communication. MVs after internalization within target cells may deliver genetic information. Human bone marrow derived mesenchymal stem cells (MSCs) and liver resident stem cells (HLSCs) were shown to release MV...

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Veröffentlicht in:	PloS one 2010-07, Vol.5 (7), p.e11803-e11803
Hauptverfasser:	Collino, Federica, Deregibus, Maria Chiara, Bruno, Stefania, Sterpone, Luca, Aghemo, Giulia, Viltono, Laura, Tetta, Ciro, Camussi, Giovanni
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis Argonaute 2 protein Biological effects Biotechnology Blotting, Western Bone marrow Bone Marrow - metabolism Cell Biology Cell cycle Cell differentiation Cell growth Cell interactions Cell survival Cells, Cultured Cluster analysis Clustering Cytoplasmic Vesicles - metabolism Cytoskeleton - metabolism Developmental Biology/Stem Cells Gene expression Granulocytes Hepatocytes Humans HuR protein Immune system In Situ Hybridization Internal medicine Internalization Liver Liver cancer Medicine Mesenchymal stem cells Mesenchymal Stem Cells - metabolism Mesenchyme MicroRNA MicroRNAs MicroRNAs - metabolism Microscopy miRNA Molecular Biology Molecular Biology/Bioinformatics mRNA stability Nuclear transport Proteins Reverse Transcriptase Polymerase Chain Reaction Ribonucleic acid Ribonucleoproteins Ribonucleoproteins - metabolism RNA RNA processing RNA transport Stem cells Stem Cells - metabolism Studies Traffic Traffic information Transcription factors Transport Tumors
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