Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children

The malaria vaccine candidate, RTS,S/AS01(E), showed promising protective efficacy in a trial of Kenyan and Tanzanian children aged 5 to 17 months. Here we report on the vaccine's safety and tolerability. The experimental design was a Phase 2b, two-centre, double-blind (observer- and participan...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2010-11, Vol.5 (11), p.e14090
Hauptverfasser:	Lusingu, John, Olotu, Ally, Leach, Amanda, Lievens, Marc, Vekemans, Johan, Olivier, Aurélie, Benns, Sarah, Olomi, Raimos, Msham, Salum, Lang, Trudie, Gould, Jayne, Hallez, Karin, Guerra, Yolanda, Njuguna, Patricia, Awuondo, Ken O, Malabeja, Anangisye, Abdul, Omar, Gesase, Samwel, Dekker, Denise, Malle, Lincoln, Ismael, Sadiki, Mturi, Neema, Drakeley, Chris J, Savarese, Barbara, Villafana, Tonya, Ballou, W Ripley, Cohen, Joe, Riley, Eleanor M, Lemnge, Martha M, Marsh, Kevin, Bejon, Philip, von Seidlein, Lorenz
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Alanine Transaminase - blood Children Creatinine - blood Dictionaries Double-Blind Method Drug dosages Ethics Experimental design Fever Fever - etiology Gastroenteritis Gastroenteritis - etiology Hematology Humans Hygiene Infant Infectious Diseases/Tropical and Travel-Associated Diseases Informed consent Kenya Kidneys Malaria Malaria Vaccines - administration & dosage Malaria Vaccines - adverse effects Malaria Vaccines - immunology Malaria, Falciparum - immunology Malaria, Falciparum - prevention & control Medical research Medicine Pain - etiology Pediatrics and Child Health Plasmodium falciparum - immunology Pneumonia - etiology Public Health and Epidemiology/Global Health Public Health and Epidemiology/Infectious Diseases Rabies Rabies Vaccines - administration & dosage Rabies Vaccines - adverse effects Rabies Vaccines - immunology Safety Sleep Stages - drug effects Studies Tanzania Vaccination - adverse effects Vaccination - methods Vaccines Vector-borne diseases
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!