Comprehensive analysis of transcript start sites in ly49 genes reveals an unexpected relationship with gene function and a lack of upstream promoters

Comprehensive analysis of the transcription start sites of the Ly49 genes of C57BL/6 mice using the oligo-capping 5'-RACE technique revealed that the genes encoding the "missing self" inhibitory receptors, Ly49A, C, G, and I, were transcribed from multiple broad regions in exon 1, in...

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Veröffentlicht in:	PloS one 2011-03, Vol.6 (3), p.e18475-e18475
Hauptverfasser:	Gays, Frances, Koh, Alan S C, Mickiewicz, Katarzyna M, Aust, Jonathan G, Brooks, Colin G
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antigens Biology Cell lines Cells, Cultured Cloning Codons Dendritic cells Exons - genetics Fluorescent Antibody Technique Fragmentation Fragments Gene expression Genes Genetic aspects Genetic research Genomes House mouse Identification Interleukin 2 Killer cells Ly-49 antigen Lymphocytes Lymphocytes T Lymphoid cells Medical schools Medicine Mice Myeloid cells Natural killer cells NK Cell Lectin-Like Receptor Subfamily A - genetics Pilot projects Promoter Regions, Genetic - genetics Promoters Receptor mechanisms Receptors Reverse Transcriptase Polymerase Chain Reaction T cells Transcription Transcription (Genetics) Transcription Initiation Site
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