CD25 Appears Non Essential for Human Peripheral Treg Maintenance In Vivo

Background IL-2 has been reported to be critical for peripheral Treg survival in mouse models. Here, we examined Treg maintenance in a series of paediatric liver transplant recipients who received basiliximab, a therapeutic anti-CD25 monoclonal antibody. Methodology/Principal Findings FoxP3+ CD4 T c...

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Veröffentlicht in:	PloS one 2010-07, Vol.5 (7), p.e11784
Hauptverfasser:	de Goër de Herve, Marie-Ghislaine, Gonzales, Emmanuel, Hendel-Chavez, Houria, Décline, Jean-Luc, Mourier, Olivia, Abbed, Karim, Jacquemin, Emmanuel, Taoufik, Yassine
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Animal models CD25 antigen CD4 antigen Cytometry Flow cytometry Food allergies Food hypersensitivity Foxp3 protein Gastroenterology Gastroenterology and Hepatology/Hepatology Gene expression Grafting Immunology Immunology/Immunomodulation Interleukin 2 Interleukin 2 receptors Kinases Liver Liver transplantation Liver transplants Lymphocytes Lymphocytes T Maintenance Microemulsions Monoclonal antibodies Pediatrics Transplants & implants
Online-Zugang:	Volltext
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