Influence of caloric restriction on constitutive expression of NF-κB in an experimental mouse astrocytoma

Many of the current standard therapies employed for the management of primary malignant brain cancers are largely viewed as palliative, ultimately because these conventional strategies have been shown, in many instances, to decrease patient quality of life while only offering a modest increase in th...

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Veröffentlicht in:	PloS one 2011-03, Vol.6 (3), p.e18085-e18085
Hauptverfasser:	Mulrooney, Tiernan J, Marsh, Jeremy, Urits, Ivan, Seyfried, Thomas N, Mukherjee, Purna
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Hydroxybutyric Acid - metabolism Aging Angiogenesis Animals Antigens, CD - metabolism Antigens, Differentiation, Myelomonocytic - metabolism Apoptosis-inducing factor Astrocytoma Astrocytoma - blood Astrocytoma - metabolism Astrocytoma - pathology Biology Blood Glucose - metabolism Blotting, Western Body Weight Brain Brain - metabolism Brain - pathology Brain cancer Brain tumors Breast cancer Calcium-Binding Proteins - metabolism Caloric Restriction Cancer Cell Nucleus - metabolism Cell Proliferation Cell survival Cyclooxygenase 2 - metabolism Cyclooxygenase-2 Cytokines Cytosol - metabolism Dietary restrictions Disease control DNA, Neoplasm - metabolism Edema Fibroblasts Gene expression Genes Gram-positive bacteria I-kappa B Proteins - metabolism In vivo methods and tests Inflammation Inflammation Mediators - metabolism Kinases Macrophage inflammatory protein Macrophages Male Medicine Metabolic disorders Mice Mice, Inbred C57BL Microfilament Proteins - metabolism Morbidity NF-kappa B - metabolism NF-κB protein Phosphorylation Promoter Regions, Genetic - genetics Prostate Protein Binding Proteins Quality of life Survival Transcription activation Tumors Vascular endothelial growth factor
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