Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human

Background Studies in mice have shown that PPARα is an important regulator of hepatic lipid metabolism and the acute phase response. However, little information is available on the role of PPARα in human liver. Here we set out to compare the function of PPARα in mouse and human hepatocytes via analy...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2009-08, Vol.4 (8), p.e6796
Hauptverfasser:	Rakhshandehroo, M, Hooiveld, G.J.E.J, Müller, M.R, Kersten, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Apolipoproteins CD36 antigen Comparative analysis Cytochrome P450 Diabetes and Endocrinology Gene expression Gene regulation Genes Genetics and Genomics Genetics and Genomics/Pharmacogenomics Genomics Gluconeogenesis Glycolysis Hepatocytes Kinases Lipid metabolism Liver Metabolism Mitochondrial uncoupling protein 2 Nutrition Rodents Target recognition Xenobiotics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!