The effects of overexpression of histamine releasing factor (HRF) in a transgenic mouse model

Asthma is a disease that affects all ages, races and ethnic groups. Its incidence is increasing both in Westernized countries and underdeveloped countries. It involves inflammation, genetics and environment and therefore, proteins that exacerbate the asthmatic, allergic phenotype are important. Our...

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Veröffentlicht in:	PloS one 2010-06, Vol.5 (6), p.e11077-e11077
Hauptverfasser:	Yeh, Yueh-Chiao, Xie, Liping, Langdon, Jacqueline M, Myers, Allen C, Oh, Sun-Young, Zhu, Zhou, Macdonald, Susan M
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Analysis Animals Asthma Asthma - genetics Asthma - metabolism B cells Base Sequence Biology Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Blotting, Western Bronchoalveolar Lavage Fluid Cell Biology Cytokines Developing countries Disease Models, Animal DNA Primers Eosinophils Epithelial cells Food allergies Genetic engineering Genetics Green Fluorescent Proteins - genetics Histamine Humans Hypersensitivity Immunoglobulin E Immunology/Allergy and Hypersensitivity Inflammation Interleukin 13 Interleukin 4 LDCs Leukocytes (basophilic) Leukocytes (eosinophilic) Lungs Macrophages Medicine Mice Mice, Transgenic Microscopy, Fluorescence Minority & ethnic groups Molecular Biology Monocyte chemoattractant protein 1 mRNA Phosphorylation Promoter Regions, Genetic Proteins Respiratory Medicine/Asthma Reverse Transcriptase Polymerase Chain Reaction Rodents Statistical analysis Transgenic mice Uteroglobin - genetics
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