Myostatin expression, lymphocyte population, and potential cytokine production correlate with predisposition to high-fat diet induced obesity in mice

A strong relationship exists between increased inflammatory cytokines and muscle insulin resistance in obesity. This study focused on identifying a relationship between metabolic propensity and myostatin expression in muscle and spleen cells in response to high-fat diet intake. Using a comparative a...

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Veröffentlicht in:PloS one 2010-09, Vol.5 (9), p.e12928-e12928
Hauptverfasser: Lyons, Jeri-Anne, Haring, Jodie S, Biga, Peggy R
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Sprache:eng
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