Basic fibroblast growth factor activates MEK/ERK cell signaling pathway and stimulates the proliferation of chicken primordial germ cells

Long-term maintenance of avian primordial germ cells (PGCs) in vitro has tremendous potential because it can be used to deepen our understanding of the biology of PGCs. A transgenic bioreactor based on the unique migration of PGCs toward the recipients' sex cord via the bloodstream and thereby...

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Veröffentlicht in:	PloS one 2010-09, Vol.5 (9), p.e12968-e12968
Hauptverfasser:	Choi, Jin Won, Kim, Sujung, Kim, Tae Min, Kim, Young Min, Seo, Hee Won, Park, Tae Sub, Jeong, Jae-Wook, Song, Gwonhwa, Han, Jae Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Agricultural biotechnology Analysis Animals Apoptosis Bioreactors Birds Blood Cell Biology/Cell Growth and Division Cell Biology/Cell Signaling Cell culture Cell Differentiation Cell growth Cell Proliferation Cells, Cultured Cellular signal transduction Chickens Developmental Biology/Embryology Developmental Biology/Germ Cells Embryos Epidermal growth factor Extracellular signal-regulated kinase Extracellular Signal-Regulated MAP Kinases - genetics Extracellular Signal-Regulated MAP Kinases - metabolism Fibroblast growth factor 2 Fibroblast Growth Factor 2 - metabolism Fibroblast growth factors Fibroblasts Genetic engineering Genetics and Genomics/Animal Genetics Genetics and Genomics/Gene Expression Germ cells Germ Cells - cytology Germ Cells - enzymology Germ Cells - metabolism Growth factors Heat shock proteins Humans Kinases MAP kinase MAP Kinase Kinase Kinases - genetics MAP Kinase Kinase Kinases - metabolism Mitogens Morphology Phosphatase Phosphorylation Poultry Prostate cancer Protein kinase Signal Transduction Signaling Stem cells Survival Telomerase
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