Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing

Follicular lymphoma (FL) is a form of non-Hodgkin's lymphoma (NHL) that arises from germinal center (GC) B-cells. Despite the significant advances in immunotherapy, FL is still not curable. Beyond transcriptional profiling and genomics datasets, there currently is no epigenome-scale dataset or...

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Veröffentlicht in:	PloS one 2010-09, Vol.5 (9), p.e13020
Hauptverfasser:	Choi, Jeong-Hyeon, Li, Yajun, Guo, Juyuan, Pei, Lirong, Rauch, Tibor A, Kramer, Robin S, Macmil, Simone L, Wiley, Graham B, Bennett, Lynda B, Schnabel, Jennifer L, Taylor, Kristen H, Kim, Sun, Xu, Dong, Sreekumar, Arun, Pfeifer, Gerd P, Roe, Bruce A, Caldwell, Charles W, Bhalla, Kapil N, Shi, Huidong
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Analysis B cells B-Lymphocytes - metabolism Binding proteins Bioinformatics Bisulfite Cancer Care and treatment CD19 antigen Data processing Deoxyribonucleic acid DNA DNA fingerprinting DNA Methylation DNA sequencing Enrichment Epigenetic inheritance Epigenetics Gene expression Gene mapping Gene sequencing Genes Genetic aspects Genetics and Genomics/Epigenetics Genetics and Genomics/Gene Expression Genome, Human Genome-Wide Association Study Genomes Genomics Hematology Humans Immunotherapy Lung cancer Lymphocytes B Lymphoma Lymphoma, Follicular - genetics Lymphoma, Follicular - metabolism Medical research Methylation Non-Hodgkin's lymphoma Non-Hodgkin's lymphomas Nucleotide sequence Oncology/Hematological Malignancies Pathology Promoter Regions, Genetic Prostate cancer Protein binding Protein expression Proteins Sequence Analysis, DNA - methods Sulfites Sulfites - chemistry Target recognition Transcription Tumors
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