The roles and acting mechanism of Caenorhabditis elegans DNase II genes in apoptotic dna degradation and development

DNase II enzymes are acidic endonucleases that have been implicated in mediating apoptotic DNA degradation, a critical cell death execution event. C. elegans genome contains three DNase II homologues, NUC-1, CRN-6, and CRN-7, but their expression patterns, acting sites, and roles in apoptotic DNA de...

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Veröffentlicht in:	PloS one 2009-10, Vol.4 (10), p.e7348-e7348
Hauptverfasser:	Lai, Huey-Jen, Lo, Szecheng J, Kage-Nakadai, Eriko, Mitani, Shohei, Xue, Ding
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Animals, Genetically Modified Apoptosis Bacteria Biodegradation Caenorhabditis elegans Caenorhabditis elegans - physiology Cell Biology/Cellular Death and Stress Responses Cell death Cloning Degradation Deoxyribonuclease Deoxyribonucleases - metabolism Deoxyribonucleic acid Developmental biology Disruption DNA DNA - chemistry DNA binding proteins DNA Damage Drosophila Endodeoxyribonucleases - chemistry Endodeoxyribonucleases - metabolism Endodeoxyribonucleases - physiology Enzymes Gene expression Gene Expression Regulation Genes Genetic research Genetics Genetics and Genomics/Chromosome Biology Genome Genomes Genomics Green Fluorescent Proteins - metabolism Homology Insects Intestinal Mucosa - metabolism Intestine Kinetics Mammals Molecular Biology/Chromosome Structure Nematodes Nervous system Nuclease Nucleases Phagocytes Phagocytes - metabolism Physiology Rodents Science Worms
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