Linking power Doppler ultrasound to the presence of th17 cells in the rheumatoid arthritis joint

Power Doppler ultrasound (PDUS) is increasingly used to assess synovitis in Rheumatoid Arthritis (RA). Prior studies have shown correlations between PDUS scores and vessel counts, but relationships with T cell immunopathology have not been described. PBMC were isolated from healthy controls (HC) or...

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Veröffentlicht in:	PloS one 2010-09, Vol.5 (9), p.e12516
Hauptverfasser:	Gullick, Nicola J, Evans, Hayley G, Church, Leigh D, Jayaraj, David M, Filer, Andrew, Kirkham, Bruce W, Taams, Leonie S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Angiogenesis Arthritis Arthritis, Rheumatoid - diagnosis Arthritis, Rheumatoid - diagnostic imaging Arthritis, Rheumatoid - immunology Autoimmune diseases B cells Biomedical research Blood Blood flow Case-Control Studies CD4 antigen Cell culture Cells, Cultured Cellular biology Correlation analysis Cytokines Cytokines - immunology Cytometry Doppler effect Enzyme-linked immunosorbent assay Female Fibroblasts Flow cytometry Helper cells Hospitals Humans Immunology Immunology/Immune Response Inflammation Interleukin 1 Interleukin 17 Ionomycin Joint diseases Joints - diagnostic imaging Joints - immunology Knee Lymphocytes Lymphocytes T Male Medical research Middle Aged Pathogenesis Patients Peripheral blood mononuclear cells Radiology and Medical Imaging/Ultrasonography Remission Rheumatoid arthritis Rheumatoid factor Rheumatology Rheumatology/Imaging and Biomarkers Rheumatology/Rheumatoid Arthritis Synovial fluid Synovial Fluid - immunology Synovitis Synovitis - diagnostic imaging Synovitis - immunology T cells Th17 Cells - immunology Tumor necrosis factor Tumor necrosis factor-TNF Tumor necrosis factor-α Ultrasonic imaging Ultrasonography, Doppler Ultrasound Vascular endothelial growth factor γ-Interferon
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