Rules governing selective protein carbonylation

Carbonyl derivatives are mainly formed by direct metal-catalysed oxidation (MCO) attacks on the amino-acid side chains of proline, arginine, lysine and threonine residues. For reasons unknown, only some proteins are prone to carbonylation. we used mass spectrometry analysis to identify carbonylated...

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Veröffentlicht in:	PloS one 2009-10, Vol.4 (10), p.e7269-e7269
Hauptverfasser:	Maisonneuve, Etienne, Ducret, Adrien, Khoueiry, Pierre, Lignon, Sabrina, Longhi, Sonia, Talla, Emmanuel, Dukan, Sam
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Analysis Arginine Arginine - chemistry Bacillus subtilis - metabolism Biochemistry Biochemistry - methods Biochemistry, Molecular Biology Biochemistry/Bioinformatics Bioinformatics Carbon - chemistry Carbonyls Catalysis Computational Biology/Sequence Motif Analysis E coli Escherichia coli Escherichia coli - metabolism Genomes Humans Life Sciences Lysine Lysine - chemistry Mass spectrometry Mass Spectrometry - methods Mass spectroscopy Mathematical models Metals - chemistry Microbiology Molecular Sequence Data Oxidation Oxygen - chemistry Phylogenetics Polypeptides Prediction models Proline Proline - chemistry Protein Carbonylation Proteins Proteins - chemistry Proteomes Serum Albumin - chemistry Threonine Threonine - chemistry
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