Understanding PRRSV infection in porcine lung based on genome-wide transcriptome response identified by deep sequencing

Porcine reproductive and respiratory syndrome (PRRS) has been one of the most economically important diseases affecting swine industry worldwide and causes great economic losses each year. PRRS virus (PRRSV) replicates mainly in porcine alveolar macrophages (PAMs) and dendritic cells (DCs) and devel...

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Veröffentlicht in:	PloS one 2010-06, Vol.5 (6), p.e11377-e11377
Hauptverfasser:	Xiao, Shuqi, Jia, Jianyu, Mo, Delin, Wang, Qiwei, Qin, Limei, He, Zuyong, Zhao, Xiao, Huang, Yuankai, Li, Anning, Yu, Jingwei, Niu, Yuna, Liu, Xiaohong, Chen, Yaosheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveoli Animals Antibodies Antigens Antiviral agents Apoptosis Base Sequence Cell adhesion molecules Chemokines Complement activation Cytokines Dendritic cells Development and progression Disease DNA Primers Economic impact Gene expression Gene Expression Profiling Gene sequencing Genes Genes, Viral Genetic aspects Genetics and Genomics/Functional Genomics Genomes Genomics Health aspects Hogs Immune response Immune system Immunoglobulins Immunology Immunology/Immune Response Immunosuppression Immunotherapy Infection Infections Inflammation Influenza Innate immunity Laboratories Life sciences Livestock Lungs Macrophages Mitochondria Molecular modelling Nitric oxide Pathogenesis Pneumonia Polymerase Chain Reaction Porcine Reproductive and Respiratory Syndrome - genetics Porcine respiratory and reproductive syndrome virus Porcine respiratory and reproductive syndrome virus - genetics Porcine respiratory and reproductive syndrome virus - physiology Pork industry Quantitative Trait Loci Sepsis Swine Systems analysis Transcription Transcription (Genetics) Virology/Effects of Virus Infection on Host Gene Expression Virology/Host Antiviral Responses Virology/Mechanisms of Resistance and Susceptibility, including Host Genetics Viruses
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