The 3'-phosphoadenosine 5'-phosphosulfate transporters, PAPST1 and 2, contribute to the maintenance and differentiation of mouse embryonic stem cells

Recently, we have identified two 3'-phosphoadenosine 5'-phosphosulfate (PAPS) transporters (PAPST1 and PAPST2), which contribute to PAPS transport into the Golgi, in both human and Drosophila. Mutation and RNA interference (RNAi) of the Drosophila PAPST have shown the importance of PAPST-d...

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Veröffentlicht in:	PloS one 2009-12, Vol.4 (12), p.e8262-e8262
Hauptverfasser:	Sasaki, Norihiko, Hirano, Takuya, Ichimiya, Tomomi, Wakao, Masahiro, Hirano, Kazumi, Kinoshita-Toyoda, Akiko, Toyoda, Hidenao, Suda, Yasuo, Nishihara, Shoko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anion Transport Proteins - genetics Anion Transport Proteins - metabolism Bone morphogenetic proteins Carbohydrates Cell Biology/Cell Signaling Cell Biology/Extra-Cellular Matrix Cell Differentiation Cell Proliferation Cell self-renewal Chains Chondroitin sulfate Chondroitin Sulfates - metabolism Defects Developmental Biology Developmental Biology/Stem Cells Differentiation Down-Regulation Drosophila Embryo cells Embryo, Mammalian - cytology Embryonic stem cells Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Embryos Gene expression Gene Knockdown Techniques Germ Layers - cytology Golgi apparatus Heparan sulfate Heparitin Sulfate - metabolism Kinases Kinetics Maintenance Mice Models, Biological Mutation N-Deacetylase N-deacetylase/N-sulfotransferase N-sulfotransferase Neurogenesis Phosphoadenosine Phosphosulfate - metabolism Proteins Reduction Ribonucleic acid RNA RNA, Messenger - genetics RNA, Messenger - metabolism RNA-mediated interference Signal Transduction Signaling Stem cell transplantation Stem cells Substrate Specificity Sulfates Sulfates - metabolism Sulfation Sulfotransferase Transport Wnt protein Yeast
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