Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping

Actin capping and cross-linking proteins regulate the dynamics and architectures of different cellular protrusions. Eps8 is the founding member of a unique family of capping proteins capable of side-binding and bundling actin filaments. However, the structural basis through which Eps8 exerts these f...

Ausführliche Beschreibung