Fetuin-A/albumin-mineral complexes resembling serum calcium granules and putative nanobacteria: demonstration of a dual inhibition-seeding concept

Serum-derived granulations and purported nanobacteria (NB) are pleomorphic apatite structures shown to resemble calcium granules widely distributed in nature. They appear to be assembled through a dual inhibitory-seeding mechanism involving proteinaceous factors, as determined by protease (trypsin a...

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Veröffentlicht in:	PloS one 2009-11, Vol.4 (11), p.e8058-e8058
Hauptverfasser:	Wu, Cheng-Yeu, Martel, Jan, Young, David, Young, John D
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumin Albumins - metabolism alpha-Fetoproteins - metabolism Analysis Apatite Apatites - chemistry Calcification Calcification (ectopic) Calcium Calcium (blood) Calcium - chemistry Calcium phosphates Cell culture Chymotrypsin Coalescing Crystal structure Crystallization Crystals Deactivation Gel electrophoresis Gels - chemistry Genetic transformation Granular materials Granulation Granules Heat inactivation Hematology Hot Temperature Humans Inactivation Infectious Diseases Infectious Diseases/Bacterial Infections Infectious Diseases/Urological Infections Kinetics Laboratories Lipids Microbiology Microbiology/Medical Microbiology Microbiology/Microbial Growth and Development Microorganisms Microscopy Microscopy, Electron, Transmission - methods Mineral particles Mineralization Multilayers Nanomaterials Nanoparticles Nanoparticles - chemistry Nanotechnology - methods Nuclei Particulates Pathology Peptide Hydrolases - chemistry Phosphate minerals Phosphates Phosphates - chemistry Physiology Physiology/Renal, Fluid, and Electrolyte Physiology Proteases Protein Conformation Proteins Seeding Smooth muscle Spectrometry, X-Ray Emission - methods Spectrum Analysis, Raman - methods Spindles Transformation Trypsin Urology
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