Comparative effects of heterologous TRPV1 and TRPM8 expression in rat hippocampal neurons

Heterologous channel expression can be used to control activity in select neuronal populations, thus expanding the tools available to modern neuroscience. However, the secondary effects of exogenous channel expression are often left unexplored. We expressed two transient receptor potential (TRP) cha...

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Veröffentlicht in:	PloS one 2009-12, Vol.4 (12), p.e8166-e8166
Hauptverfasser:	Crawford, Devon C, Moulder, Krista L, Gereau, 4th, Robert W, Story, Gina M, Mennerick, Steven
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Anesthesiology Animals Calcium Capsaicin - pharmacology Capsaicin receptors Cell survival Channels Chlorides Comparative analysis Depolarization Enzymes Hippocampus Hippocampus - cytology Ion Channel Gating - drug effects Ligands Light Localization Membrane potential Menthol - pharmacology Nervous system Neurobiology Neurons Neurons - drug effects Neurons - metabolism Neurophysiology Neuroscience/Neurodevelopment Neuroscience/Neuronal and Glial Cell Biology Neuroscience/Neuronal Signaling Mechanisms Neurosciences Neurotransmitter Agents - secretion Pain Physiology/Neuronal Signaling Mechanisms Potassium chloride Psychiatry Rats Rodents Ruthenium Red - metabolism Senses Signal transduction Signaling Synaptic transmission Synaptic Transmission - drug effects Tetrodotoxin - pharmacology Toxicity Transfection Transient receptor potential proteins TRPM Cation Channels - agonists TRPM Cation Channels - metabolism TRPV Cation Channels - agonists TRPV Cation Channels - metabolism
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