Human Th1 cells that express CD300a are polyfunctional and after stimulation up-regulate the T-box transcription factor eomesodermin

Human naïve CD4 T cells express low levels of the immunomodulatory receptor CD300a, whereas effector/memory CD4 cells can be either CD300a(+) or CD300a(-). This suggested that CD300a expression could define a specific subset within the effector/memory CD4 T cell subpopulations. In fact, ex vivo anal...

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Veröffentlicht in:PloS one 2010-05, Vol.5 (5), p.e10636
Hauptverfasser: Narayanan, Sriram, Silva, Rodolfo, Peruzzi, Giovanna, Alvarez, Yelina, Simhadri, Venkateswara R, Debell, Karen, Coligan, John E, Borrego, Francisco
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Sprache:eng
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