Three-dimensional analysis of a viral RNA replication complex reveals a virus-induced mini-organelle

Positive-strand RNA viruses are the largest genetic class of viruses and include many serious human pathogens. All positive-strand RNA viruses replicate their genomes in association with intracellular membrane rearrangements such as single- or double-membrane vesicles. However, the exact sites of RN...

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Veröffentlicht in:	PLoS biology 2007-09, Vol.5 (9), p.e220-e220
Hauptverfasser:	Kopek, Benjamin G, Perkins, Guy, Miller, David J, Ellisman, Mark H, Ahlquist, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Cell organelles Cytoplasm Drosophila - cytology Drosophila - virology Genomes Imaging, Three-Dimensional Medical imaging Microscopy Microscopy, Electron Mitochondrial Membranes - virology Nodaviridae Organelles - virology Proteins Ribonucleic acid RNA RNA viruses RNA, Viral - biosynthesis Tomography Virology Virus Replication Viruses
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