Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo

Positional identities along the anterior-posterior axis of the vertebrate nervous system are assigned during gastrulation by multiple posteriorizing signals, including retinoic acid (RA), fibroblast growth factors (Fgfs), and Wnts. Experimental evidence has suggested that RA, which is produced in pa...

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