miR-148 regulates Mitf in melanoma cells

The Microphthalmia associated transcription factor (Mitf) is an important regulator in melanocyte development and has been shown to be involved in melanoma progression. The current model for the role of Mitf in melanoma assumes that the total activity of the protein is tightly regulated in order to...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2010-07, Vol.5 (7), p.e11574
Hauptverfasser:	Haflidadóttir, Benedikta S, Bergsteinsdóttir, Kristín, Praetorius, Christian, Steingrímsson, Eiríkur
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions 3' Untranslated Regions - genetics Analysis Animals Apoptosis Binding Sites Biochemistry Blotting, Western Cancer Cell cycle Cell growth Cell Line Cell proliferation Cloning Conserved sequence Developmental Biology Gene expression Gene Expression Regulation, Neoplastic - genetics Gene Expression Regulation, Neoplastic - physiology Genomes Genomics Humans Medicine Melanocytes Melanoma Melanoma - genetics Melanoma - metabolism Mice Microphthalmia-associated transcription factor Microphthalmia-Associated Transcription Factor - genetics Microphthalmia-Associated Transcription Factor - metabolism MicroRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA Molecular biology Molecular Biology/mRNA Stability Mutagenesis Mutation Oncology/Skin Cancers Polymerase Chain Reaction Post-translation Protection and preservation Proteins Reverse Transcriptase Polymerase Chain Reaction Splicing Transcription factors Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!