Ablation of PGC-1[beta] Results in Defective Mitochondrial Activity, Thermogenesis, Hepatic Function, and Cardiac Performance: e369

The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator-1β (PGC-1β) has been implicated in important metabolic processes. A mouse lacking PGC-1β (PGC1βKO) was generated and phenotyped using physiological, molecular, and bioinformatic approaches. PGC1βKO mice are...

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Veröffentlicht in:	PLoS biology 2006-11, Vol.4 (11)
Hauptverfasser:	Lelliott, Christopher J, Medina-Gomez, Gema, Petrovic, Natasa, Kis, Adrienn, Feldmann, Helena M, Bjursell, Mikael, Parker, Nadeene, Curtis, Keira, Campbell, Mark, Hu, Ping, Zhang, Dongfang, Litwin, Sheldon E, Zaha, Vlad G, Fountain, Kimberly T, Boudina, Sihem, Jimenez-Linan, Mercedes, Blount, Margaret, Lopez, Miguel, Meirhaeghe, Aline, Bohlooly-Y, Mohammad, Storlien, Leonard, Strömstedt, Maria, Snaith, Michael, Oresic, Matej, Abel, E Dale, Cannon, Barbara, Vidal-Puig, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Cholesterol Cold Diet Fatty acids Gene expression Musculoskeletal system Proteins Rodents Stem cells
Online-Zugang:	Volltext
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