Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes

Candidate genes of psychological importance include 5HT2A, 5HT2C, and COMT, implicated in the serotonin, noradrenaline and dopamine pathways, which also may be involved in regulation of energy balance. We investigated the associations of single nucleotide polymorphisms (SNPs) of these genes with obe...

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Veröffentlicht in:	PloS one 2009-08, Vol.4 (8), p.e6696-e6696
Hauptverfasser:	Kring, Sofia I I, Werge, Thomas, Holst, Claus, Toubro, Søren, Astrup, Arne, Hansen, Torben, Pedersen, Oluf, Sørensen, Thorkild I A
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Age Alleles Analysis Anthropometry Behavior disorders Blood pressure Body fat Body mass Body mass index Catechol O-Methyltransferase - genetics Cholesterol Diabetes Diabetes and Endocrinology/Type 2 Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - genetics Dopamine Energy balance Genes Genetic aspects Genetics and Genomics/Genetics of Disease Genomics Genotypes Glucose Glucose tolerance Glucose Tolerance Test Homeostasis Hospitals Humans Insulin Male Mens health Metabolic syndrome Middle Aged Nervous system Noradrenaline Norepinephrine Obesity Obesity - genetics Pathways Phenols (Class of compounds) Phenotype Physiological aspects Physiology Polls & surveys Polymorphism, Single Nucleotide Preventive medicine Public Health and Epidemiology/Epidemiology Receptor, Serotonin, 5-HT2A - genetics Receptor, Serotonin, 5-HT2C - genetics Regression analysis Regulation Serotonin Serotonin S2 receptors Single nucleotide polymorphisms Single-nucleotide polymorphism Studies Surveys Type 2 diabetes Weight control
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