Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease

DNA methylation is capable of modulating coordinate expression of large numbers of genes across many different pathways, and may therefore warrant investigation for their potential role between genes and disease phenotype. In a rare set of monozygotic twins discordant for Alzheimer's disease (A...

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Veröffentlicht in:	PloS one 2009-08, Vol.4 (8), p.e6617-e6617
Hauptverfasser:	Mastroeni, Diego, McKee, Ann, Grover, Andrew, Rogers, Joseph, Coleman, Paul D
Format:	Artikel
Sprache:	eng
Schlagworte:	Advertising executives Alzheimer Disease - genetics Alzheimer Disease - pathology Alzheimer's disease Cell Biology/Neuronal and Glial Cell Biology Cerebral Cortex - metabolism Cerebral Cortex - pathology Deoxyribonucleic acid Discordance DNA DNA Methylation Epigenesis, Genetic Epigenetic inheritance Epigenetics Gene expression Genes Genetic aspects Humans Methylation Neurodegenerative diseases Neurons Neurons - metabolism Neuroscience/Neurobiology of Disease and Regeneration Neuroscience/Neuronal and Glial Cell Biology Phenotype Ricinus communis Stem cells Twins Twins, Monozygotic
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