Biphasic somatic A-type K channel downregulation mediates intrinsic plasticity in hippocampal CA1 pyramidal neurons

Since its original description, the induction of synaptic long-term potentiation (LTP) has been known to be accompanied by a lasting increase in the intrinsic excitability (intrinsic plasticity) of hippocampal neurons. Recent evidence shows that dendritic excitability can be enhanced by an activity-...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2009-08, Vol.4 (8), p.e6549-e6549
Hauptverfasser:	Jung, Sung-Cherl, Hoffman, Dax A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Back propagation Biophysics Biophysics/Cell Signaling and Trafficking Structures Channel gating Channels Clathrin Deactivation Dendritic plasticity Down-Regulation Endocytosis Excitability Excitation Excitatory postsynaptic potentials Hippocampal plasticity Hippocampus Hippocampus - cytology Hippocampus - physiology Hyperpolarization Inactivation Laboratories Long-Term Potentiation Neuronal Plasticity - physiology Neurons Neuroscience Neuroscience/Neuronal Signaling Mechanisms Patch-Clamp Techniques Plastic properties Plasticity Potassium Potassium channels Potassium Channels - physiology Potentiation Pyramidal cells Pyramidal Cells - physiology Rats Rats, Sprague-Dawley Rodents
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!