Immunity promotes virulence evolution in a malaria model

Evolutionary models predict that host immunity will shape the evolution of parasite virulence. While some assumptions of these models have been tested, the actual evolutionary outcome of immune selection on virulence has not. Using the mouse malaria model, Plasmodium chabaudi, we experimentally test...

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Veröffentlicht in:	PLoS biology 2004-09, Vol.2 (9), p.E230
Hauptverfasser:	Mackinnon, Margaret J, Read, Andrew F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Evolution Blood Colleges & universities Competition Evolution Experiments Female Genetics Host-Parasite Interactions Immune System Immunology Infectious Diseases Insect Bites and Stings Malaria - immunology Malaria - parasitology Male Mice Mice, Inbred C57BL Microbiology Models, Biological Mosquitoes Mus (Mouse) Parasites Plasmodium Plasmodium chabaudi Plasmodium chabaudi - pathogenicity Population Theory Time Factors Virulence Zoology
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