Protein array profiling of tic patient sera reveals a broad range and enhanced immune response against Group A Streptococcus antigens

The human pathogen Group A Streptococcus (Streptococcus pyogenes, GAS) is widely recognized as a major cause of common pharyngitis as well as of severe invasive diseases and non-suppurative sequelae associated with the existence of GAS antigens eliciting host autoantibodies. It has been proposed tha...

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Veröffentlicht in:	PloS one 2009-07, Vol.4 (7), p.e6332-e6332
Hauptverfasser:	Bombaci, Mauro, Grifantini, Renata, Mora, Marirosa, Reguzzi, Valerio, Petracca, Roberto, Meoni, Eva, Balloni, Sergio, Zingaretti, Chiara, Falugi, Fabiana, Manetti, Andrea G O, Margarit, Immaculada, Musser, James M, Cardona, Francesco, Orefici, Graziella, Grandi, Guido, Bensi, Giuliano
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescents Analysis Antibody response Antigens Antigens, Bacterial - immunology Autoantibodies Autoimmunity Brain research Case-Control Studies Cellulose esters Cellulose nitrate Child Childhood mental disorders Children Children & youth Chlamydia Chlamydia pneumoniae Comparative analysis Complications Disorders Enzymes Handbooks Health aspects Humans Hypotheses Immune response Immune system Immunogenicity Immunoglobulins Immunology Immunology/Immunity to Infections Infection Infections Infectious Diseases Infectious Diseases/Bacterial Infections Infectious Diseases/Infectious Diseases of the Nervous System Maximum likelihood method Mental disorders Microbiology Microbiology/Cellular Microbiology and Pathogenesis Microbiology/Immunity to Infections Movement disorders Neurochemistry Neurological Disorders/Neuropsychiatric Disorders Neuroses Obsessive compulsive disorder Patients Pattern recognition Pharyngitis Pharyngitis - blood Pharyngitis - immunology Protein Array Analysis Protein arrays Proteins Psychiatry Recombinant proteins Rheumatic fever Streptococcal Infections - blood Streptococcal Infections - immunology Streptococcus Streptococcus infections Streptococcus pyogenes - immunology Tics - blood Tourette syndrome Vaccines
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