Mitochondrial haplogroups and control region polymorphisms are not associated with prostate cancer in Middle European Caucasians

Besides being responsible for energy production in the cell, mitochondria are central players in apoptosis as well as the main source of harmful reactive oxygen species. Therefore, it can be hypothesised that sequence variation in the mitochondrial genome is a contributing factor to the etiology of...

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Veröffentlicht in:	PloS one 2009-07, Vol.4 (7), p.e6370-e6370
Hauptverfasser:	Mueller, Edith E, Eder, Waltraud, Mayr, Johannes A, Paulweber, Bernhard, Sperl, Wolfgang, Horninger, Wolfgang, Klocker, Helmut, Kofler, Barbara
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antigens Apoptosis Base Sequence Biopsy Breast cancer Cancer Cancer research Deoxyribonucleic acid Development and progression Disease DNA DNA Primers DNA sequencing Enzymes Etiology European Continental Ancestry Group Gene sequencing Genetic aspects Genetic polymorphisms Genetics and Genomics/Cancer Genetics Genetics and Genomics/Population Genetics Genomes Genomics Haplotypes Health screening Humans Kidney cancer Leukocytes (mononuclear) Male Mitochondria Mitochondrial DNA Mortality Mutation Nucleotide sequence Oncology/Prostate Cancer Oxygen Patients Pediatrics Peripheral blood mononuclear cells Phosphorylation Polymorphism, Genetic Population Prostate Prostate cancer Prostate carcinoma Prostatic Neoplasms - ethnology Prostatic Neoplasms - genetics Reactive oxygen species Urology Urology/Prostate Cancer White people Whites
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