A commensal Helicobacter sp. of the rodent intestinal flora activates TLR2 and NOD1 responses in epithelial cells

Helicobacter spp. represent a proportionately small but significant component of the normal intestinal microflora of animal hosts. Several of these intestinal Helicobacter spp. are known to induce colitis in mouse models, yet the mechanisms by which these bacteria induce intestinal inflammation are...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2009-04, Vol.4 (4), p.e5396-e5396
Hauptverfasser:	Chaouche-Drider, Nadia, Kaparakis, Maria, Karrar, Abdulgader, Fernandez, Maria-Isabel, Carneiro, Letitia A M, Viala, Jérôme, Boneca, Ivo Gomperts, Moran, Anthony P, Philpott, Dana J, Ferrero, Richard L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analysis Animal experimentation Animal models Animals Bacteria Base Sequence Cell culture Cell Line Cell lines Chemokine CXCL1 - biosynthesis Chemokine CXCL2 - biosynthesis Chemokines Chemokines, CXC - biosynthesis Coculture Techniques Colitis Colitis - etiology Colitis - immunology Colitis - metabolism Colitis - microbiology CXC chemokines Cytokines Disease Models, Animal DNA Primers - genetics Drug resistance Epithelial cells Epithelial Cells - immunology Epithelial Cells - metabolism Epithelial Cells - microbiology Flagellin - genetics Flora Gallbladder Gastroenterology and Hepatology/Gastrointestinal Infections Gastroenterology and Hepatology/Inflammatory Bowel Disease Gene expression Helicobacter Helicobacter - genetics Helicobacter - immunology Helicobacter - isolation & purification Helicobacter - pathogenicity Helicobacter Infections - etiology Helicobacter Infections - metabolism Helicobacter Infections - microbiology Helicobacter pylori Humans Immune system Immunity, Innate Immunology Immunology/Innate Immunity Infections Inflammation Inflammatory bowel disease Inflammatory diseases Interferon Intestinal microflora Intestine Intestines - immunology Intestines - microbiology Lipopolysaccharides Lipopolysaccharides - toxicity Mice Microbiology/Cellular Microbiology and Pathogenesis Microbiota (Symbiotic organisms) Mitogens Molecular Sequence Data NF-kappa B - metabolism NF-κB protein Nod1 protein Nod1 Signaling Adaptor Protein - antagonists & inhibitors Nod1 Signaling Adaptor Protein - genetics Nod1 Signaling Adaptor Protein - metabolism Pathogens Phosphorylation Plant resistance Protein expression Proteins Rodents Sequence Homology, Amino Acid Shigella Signal transduction siRNA Species Specificity TLR2 protein TLR4 protein Toll-Like Receptor 2 - genetics Toll-Like Receptor 2 - metabolism Toll-Like Receptor 4 - genetics Toll-Like Receptor 4 - metabolism Toll-like receptors Transfection Tumor necrosis factor-TNF
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!