Human TRIM gene expression in response to interferons

Tripartite motif (TRIM) proteins constitute a family of proteins that share a conserved tripartite architecture. The recent discovery of the anti-HIV activity of TRIM5alpha in primate cells has stimulated much interest in the potential role of TRIM proteins in antiviral activities and innate immunit...

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Veröffentlicht in:	PloS one 2009-03, Vol.4 (3), p.e4894
Hauptverfasser:	Carthagena, Laetitia, Bergamaschi, Anna, Luna, Joseph M, David, Annie, Uchil, Pradeep D, Margottin-Goguet, Florence, Mothes, Walther, Hazan, Uriel, Transy, Catherine, Pancino, Gianfranco, Nisole, Sébastien
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Antiviral activity Cell activation Classification Gene expression Gene Expression Regulation - drug effects Genes Genetic research HIV Human immunodeficiency virus Humans Immune response Immune system Immunity Immunology Immunotherapy Infections Innate immunity Interferon Interferons - pharmacology Life Sciences Lymphocytes Macrophages Macrophages - drug effects Macrophages - metabolism Membrane Proteins - genetics Monocytes Pathogenesis Phylogeny Promoter Regions, Genetic Proteins Reverse Transcriptase Polymerase Chain Reaction Transcription factors Viral infections Virology/Host Antiviral Responses Virology/Mechanisms of Resistance and Susceptibility, including Host Genetics Virology/Viral and Gene Regulation Viruses
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