Interleukin-32β Propagates Vascular Inflammation and Exacerbates Sepsis in a Mouse Model

Background Inflammation is associated with most diseases, which makes understanding the mechanisms of inflammation vitally important. Methodology/Principal Findings Here, we demonstrate a critical function of interleukin-32β (IL-32β) in vascular inflammation. IL-32β is present in tissues from humans...

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Veröffentlicht in:	PloS one 2010-03, Vol.5 (3), p.e9458
Hauptverfasser:	Kobayashi, Hanako, Huang, Jianhua, Ye, Fei, Shyr, Yu, Blackwell, Timothy S., Lin, P. Charles
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Angiogenesis Animal tissues Apoptosis Biology Cancer Cardiovascular Disorders/Valvular Disease Cardiovascular Disorders/Vascular Biology Cell adhesion Cell adhesion & migration Cell adhesion molecules Cloning Cytokines Endothelial cells Endothelium Genes Health care IL-1β Immunoglobulins Infiltration Inflammation Interleukins Isoforms Lungs Lymphocytes Mortality Motility NF-κB protein Oncology Permeability Positive feedback Preventive medicine Respiratory Medicine/Respiratory Infections Rodents Sepsis Serum levels Transgenic mice Tumor necrosis factor-α
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