Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface

Colonization of the human stomach by Helicobacter pylori is an important risk factor for development of gastric cancer. The H. pylori cag pathogenicity island (cag PAI) encodes components of a type IV secretion system (T4SS) that translocates the bacterial oncoprotein CagA into gastric epithelial ce...

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Veröffentlicht in:	PLoS pathogens 2011-09, Vol.7 (9), p.e1002237-e1002237
Hauptverfasser:	Shaffer, Carrie L, Gaddy, Jennifer A, Loh, John T, Johnson, Elizabeth M, Hill, Salisha, Hennig, Ewa E, McClain, Mark S, McDonald, W Hayes, Cover, Timothy L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antigens, Bacterial - metabolism Bacteria Bacterial Proteins - metabolism Bacterial Proteins - physiology Bacteriology Biology Colonization Epithelial cells Fimbriae, Bacterial - physiology Gastric cancer Genomic Islands Health aspects Helicobacter Infections - physiopathology Helicobacter pylori Helicobacter pylori - metabolism Helicobacter pylori - pathogenicity Homology Host-Pathogen Interactions - physiology Humans Infections Integrins Interleukin 8 Medicine Microbiology pathogenicity islands Pathogens Physiological aspects Pili Proteins Risk factors Scanning electron microscopy Stomach - microbiology Stomach cancer Translocation Ulcers
Online-Zugang:	Volltext
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