Two Host Factors Regulate Persistence of H7a-Specific T Cells Injected in Tumor-Bearing Mice

Background Injection of CD8 T cells primed against immunodominant minor histocompatibility antigens (MiHA) such as H7a can eradicate leukemia and solid tumors. To understand why MiHA-targeted T cells have such a potent antitumor effect it is essential to evaluate their in vivo behavior. In the prese...

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Veröffentlicht in:PloS one 2009-01, Vol.4 (1), p.e4116
Hauptverfasser: Meunier, Marie-Christine, Baron, Chantal, Perreault, Claude
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Sprache:eng
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