Angiogenic factors stimulate growth of adult neural stem cells

The ability to grow a uniform cell type from the adult central nervous system (CNS) is valuable for developing cell therapies and new strategies for drug discovery. The adult mammalian brain is a source of neural stem cells (NSC) found in both neurogenic and non-neurogenic zones but difficulties in...

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Veröffentlicht in:	PloS one 2010-02, Vol.5 (2), p.e9414-e9414
Hauptverfasser:	Androutsellis-Theotokis, Andreas, Rueger, Maria A, Park, Deric M, Boyd, Justin D, Padmanabhan, Raji, Campanati, Loraine, Stewart, Craig V, LeFranc, Yann, Plenz, Dietmar, Walbridge, Stuart, Lonser, Russell R, McKay, Ronald D G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult Stem Cells - cytology Analysis Angiogenesis Angiogenesis Inducing Agents - pharmacology Angiopoietin Angiopoietin-2 - pharmacology Animals Antigens Bone marrow Brain Brain - cytology Cancer Cell culture Cell Culture Techniques Cell Differentiation - drug effects Cell Proliferation - drug effects Cell self-renewal Cells, Cultured Central nervous system Cloning DNA-Binding Proteins - metabolism Dopamine Drug discovery Epidermal growth factor Fibroblast Growth Factors - pharmacology Fibroblasts Gene expression Haplorhini Humans Immunohistochemistry Insulin Intracellular Signaling Peptides and Proteins Laboratories Membrane Proteins - pharmacology Mental health Mice Molecular biology Nervous system Neural stem cells Neurological Disorders Neurological Disorders/Movement Disorders Neurological Disorders/Spinal Disorders Neurology Neurons Neurons - cytology Neuroscience Neuroscience/Neurobiology of Disease and Regeneration Neurosciences Notch protein Phosphorylation Rats Regeneration Rodents Signal transduction Stem cells Stem Cells - cytology Stroke Transcription Factors - metabolism Tumors
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