Effects of intermittent IL-2 alone or with peri-cycle antiretroviral therapy in early HIV infection: the STALWART study

The Study of Aldesleukin with and without antiretroviral therapy (STALWART) evaluated whether intermittent interleukin-2 (IL-2) alone or with antiretroviral therapy (ART) around IL-2 cycles increased CD4(+) counts compared to no therapy. Participants not on continuous ART with > or = 300 CD4(+) c...

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Veröffentlicht in:	PloS one 2010-02, Vol.5 (2), p.e9334
Hauptverfasser:	Tavel, Jorge A, Babiker, Abdel, Fox, Lawrence, Gey, Daniela, Lopardo, Gustavo, Markowitz, Norman, Paton, Nicholas, Wentworth, Deborah, Wyman, Nicole
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-HIV Agents - adverse effects Anti-HIV Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiretrovirals Atazanavir Sulfate Carbamates - therapeutic use CD4 antigen CD4 Lymphocyte Count Clinical outcomes Clinical trials Comparative analysis Cytokines Development and progression Disease Drug Administration Schedule Drug dosages Drug resistance Drug therapy Drug Therapy, Combination Female Fever - chemically induced Health aspects Highly active antiretroviral therapy HIV HIV (Viruses) HIV infections HIV Infections - drug therapy HIV Infections - immunology Human immunodeficiency virus Humans Hypotheses Immunology Immunology/Immunomodulation Infections Infectious Diseases Infectious Diseases/HIV Infection and AIDS Infectious Diseases/Viral Infections Interleukin 2 Interleukin-2 - adverse effects Interleukin-2 - therapeutic use Interleukins Lopinavir Male Medical research Mutation Nausea - chemically induced Oligopeptides - therapeutic use Opportunistic Infections - chemically induced Organophosphates - therapeutic use Patients Pyridines - therapeutic use Pyrimidinones - therapeutic use Randomization Ribonucleic acid Ritonavir - therapeutic use RNA Studies Sulfonamides - therapeutic use Therapy Treatment Outcome VIH (Virus)
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