High prevalence of both humoral and cellular immunity to Zaire ebolavirus among rural populations in Gabon

To better understand Zaire ebolavirus (ZEBOV) circulation and transmission to humans, we conducted a large serological survey of rural populations in Gabon, a country characterized by both epidemic and non epidemic regions. The survey lasted three years and covered 4,349 individuals from 220 randoml...

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Veröffentlicht in:	PloS one 2010-02, Vol.5 (2), p.e9126-e9126
Hauptverfasser:	Becquart, Pierre, Wauquier, Nadia, Mahlakõiv, Tanel, Nkoghe, Dieudonné, Padilla, Cindy, Souris, Marc, Ollomo, Benjamin, Gonzalez, Jean-Paul, De Lamballerie, Xavier, Kazanji, Mirdad, Leroy, Eric M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses Adolescent Adult Age Factors Antibodies, Viral - blood Aquatic ecosystems Bats CD8 antigen Cell-mediated immunity Child Child, Preschool Cytotoxicity Ebola virus Ebolavirus - immunology Ecosystems Encephalitis Enzyme-Linked Immunosorbent Assay Epidemics Exposure Fatalities Female Fever Food contamination Gabon - epidemiology Geography Grasslands Hemorrhagic Fever, Ebola - epidemiology Hemorrhagic Fever, Ebola - immunology Hemorrhagic Fever, Ebola - virology Human populations Humans Humoral immunity Immunity Immunity, Cellular - immunology Immunity, Humoral - immunology Immunization Immunoglobulin G Immunoglobulin G - blood Immunology/Immune Response Infant Infections Infectious Diseases/Epidemiology and Control of Infectious Diseases Infectious Diseases/Viral Infections Interferon-gamma - metabolism Lymphocytes Lymphocytes T Male Middle Aged Pathogenicity Pathogens Populations Prevalence Risk analysis Risk factors Rural Population - statistics & numerical data Rural populations Saliva Savannahs Seroepidemiologic Studies Serology Surveys T cell receptors T cells T-Lymphocytes - immunology T-Lymphocytes - metabolism Virology/Emerging Viral Diseases Viruses Yang, Cindy Young Adult γ-Interferon
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