Extracellular BCL2 proteins are danger-associated molecular patterns that reduce tissue damage in murine models of ischemia-reperfusion injury

Ischemia-reperfusion (I/R) injury contributes to organ dysfunction in a variety of clinical disorders, including myocardial infarction, stroke, organ transplantation, and hemorrhagic shock. Recent investigations have demonstrated that apoptosis as an important mechanism of cell death leading to orga...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2010-02, Vol.5 (2), p.e9103-e9103
Hauptverfasser:	Iwata, Akiko, Morgan-Stevenson, Vicki, Schwartz, Barbara, Liu, Li, Tupper, Joan, Zhu, Xiaodong, Harlan, John, Winn, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Animal models Animals Apoptosis Apoptosis - drug effects Cardiac muscle Cardiovascular Disorders/Myocardial Infarction Cardiovascular Disorders/Vascular Biology Cell Biology/Cellular Death and Stress Responses Cell death Cerebral infarction Coronary artery Coronary vessels Cytokines Diabetes Disease Models, Animal Gangrene Harlan, Robert Hazards Head injuries Heart Heart attack Heart diseases Hemorrhage Hepatitis Hindlimb - blood supply Hostages Humans Immune system Immunology/Innate Immunity Infarction Injury prevention Innate immunity Ischemia Laboratories Medicine Mice Mice, Inbred C57BL Mice, Knockout Minor Histocompatibility Antigens Molecular modelling Molecular Sequence Data Multiple sclerosis Muscle, Skeletal - blood supply Muscle, Skeletal - drug effects Muscles Musculoskeletal system MyD88 protein Myeloid Differentiation Factor 88 - deficiency Myeloid Differentiation Factor 88 - genetics Myocardial infarction Myocardial Ischemia - pathology Myocardial Ischemia - prevention & control Organ transplantation Ovarian cancer Oxidative stress Peptides Peptides - chemistry Peptides - pharmacology Physiology/Cardiovascular Physiology and Circulation Physiology/Integrative Physiology Proteins Proto-Oncogene Proteins - chemistry Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - pharmacology Proto-Oncogene Proteins c-bcl-2 - chemistry Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - pharmacology Rats Rats, Sprague-Dawley Receptors Recombinant Proteins - pharmacology Reperfusion Reperfusion injury Reperfusion Injury - etiology Reperfusion Injury - pathology Reperfusion Injury - prevention & control Rodents Sepsis Shock Signal Transduction Skeletal muscle Stroke Surgery TLR2 protein Toll-Like Receptor 2 - deficiency Toll-Like Receptor 2 - genetics Toll-like receptors Tourniquets - adverse effects Transplantation Traumatic brain injury
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!