Reinforcement versus fluidization in cytoskeletal mechanoresponsiveness

Every adherent eukaryotic cell exerts appreciable traction forces upon its substrate. Moreover, every resident cell within the heart, great vessels, bladder, gut or lung routinely experiences large periodic stretches. As an acute response to such stretches the cytoskeleton can stiffen, increase trac...

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Veröffentlicht in:PloS one 2009-05, Vol.4 (5), p.e5486-e5486
Hauptverfasser: Krishnan, Ramaswamy, Park, Chan Young, Lin, Yu-Chun, Mead, Jere, Jaspers, Richard T, Trepat, Xavier, Lenormand, Guillaume, Tambe, Dhananjay, Smolensky, Alexander V, Knoll, Andrew H, Butler, James P, Fredberg, Jeffrey J
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Sprache:eng
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