Genome Scan for Positive Selection in Thoroughbred Horses

Thoroughbred horses have been selected for exceptional racing performance resulting in system-wide structural and functional adaptations contributing to elite athletic phenotypes. Because selection has been recent and intense in a closed population that stems from a small number of founder animals T...

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Veröffentlicht in:	PloS one 2009-06, Vol.4 (6), p.e5767-e5767
Hauptverfasser:	Gu, Jingjing, Orr, Nick, Park, Stephen D, Katz, Lisa M, Sulimova, Galina, MacHugh, David E, Hill, Emmeline W
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actinin Adaptation Adaptations Alcohol dehydrogenase Alcoholic beverages Alleles Alpha iron animal breeding animal genetics Animal models animal physiology Animal populations Animals artificial selection autosomes Chromosomes - ultrastructure Cloning Dehydrogenase Diabetes mellitus Enrichment Exercise Fatty acids Food science Gene mapping Genes Genetic Variation Genetics Genetics and Genomics/Animal Genetics Genetics and Genomics/Comparative Genomics Genetics and Genomics/Complex Traits Genetics and Genomics/Disease Models Genetics and Genomics/Gene Function Genetics and Genomics/Genetics of Disease Genetics and Genomics/Genomics Genetics and Genomics/Physiogenomics Genetics and Genomics/Population Genetics Genome Genomes Genomics Heterozygosity Heterozygote Horses Horses - genetics Hypoxia In vivo methods and tests Insulin Iron Laboratories Life sciences Loci Medical research Metabolic disorders Metabolism Microsatellite Repeats Microsatellites Mitochondria Muscle proteins Muscle strength Muscles - metabolism Muscular strength Musculoskeletal system Natural selection Oxidation Phenotype physical activity Physical fitness Physiology Population Population genetics Positive selection Pyruvic acid Racing Racing performance selection criteria Selection, Genetic Signal transduction Signaling Skeletal muscle Statistics Structure-function relationships Tenascin Tenascin C Thoroughbred Type 2 diabetes Veterinary medicine X chromosome
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