Heterochromatic siRNAs and DDM1 Independently Silence Aberrant 5S rDNA Transcripts in Arabidopsis

5S ribosomal RNA gene repeats are arranged in heterochromatic arrays (5S rDNA) situated near the centromeres of Arabidopsis chromosomes. The chromatin remodeling factor DDM1 is known to maintain 5S rDNA methylation patterns while silencing transcription through 5S rDNA intergenic spacers (IGS). We m...

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Veröffentlicht in:	PloS one 2009-06, Vol.4 (6), p.e5932-e5932
Hauptverfasser:	Blevins, Todd, Pontes, Olga, Pikaard, Craig S, Meins, Frederick Jr
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Arabidopsis Arabidopsis - metabolism Arabidopsis Proteins - metabolism Arabidopsis thaliana Biology Biomedical research Biosynthesis Cell division Centromeres Chromatin Chromatin - chemistry Chromatin remodeling chromatin remodeling factor Chromosomes Computational Biology - methods Crosses, Genetic DDM1 protein Deoxyribonucleic acid DNA DNA methylation DNA polymerases DNA, Intergenic DNA, Ribosomal - metabolism DNA-binding proteins DNA-Binding Proteins - metabolism DNA-directed RNA polymerase Fines & penalties Flowers & plants Gene expression gene expression regulation Gene loci Gene Silencing Genes, Plant Genetics and Genomics/Epigenetics heterochromatin In Situ Hybridization, Fluorescence Methylation Models, Biological Molecular Biology/Chromatin Structure Molecular Biology/DNA Methylation Molecular Biology/Nucleolus and Nuclear Bodies Plant Biology/Plant Genetics and Gene Expression Proteins Ribonucleic acid ribosomal DNA Ribosomal RNA RNA RNA, Ribosomal, 5S - metabolism RNA, Small Interfering - metabolism RNA-directed RNA polymerase rRNA 5S Silence siRNA small interfering RNA Transcription Factors - metabolism Transcription, Genetic Trends
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