The making of a queen: TOR pathway is a key player in diphenic caste development

Honey bees (Apis mellifera) provide a principal example of diphenic development. Excess feeding of female larvae results in queens (large reproductives). Moderate diet yields workers (small helpers). The signaling pathway that links provisioning to female developmental fate is not understood, yet we...

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Veröffentlicht in:	PloS one 2007-06, Vol.2 (6), p.e509-e509
Hauptverfasser:	Patel, Avani, Fondrk, M Kim, Kaftanoglu, Osman, Emore, Christine, Hunt, Greg, Frederick, Katy, Amdam, Gro V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal behavior Animals Apis mellifera Bees Bees - physiology Behavior, Animal - physiology Caste determination Caste differentiation Developmental Biology/Developmental Evolution Dimorphism Drosophila European honeybee Evolutionary Biology/Genomics Female Females Foraging behavior Gene expression Gene Expression Regulation, Developmental Genetics and Genomics/Functional Genomics Genetics and Genomics/Gene Function Hierarchy, Social Honey Insects Insulin Intracellular Signaling Peptides and Proteins - antagonists & inhibitors Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Laboratories Larva - growth & development Larva - metabolism Larvae Life sciences Metabolism Morphology Nutrients Pharmacology Protein-Serine-Threonine Kinases - antagonists & inhibitors Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Provisioning Queens Rapamycin Ribonucleic acid RNA RNA, Small Interfering - pharmacology RNA-mediated interference Signal transduction Sirolimus - pharmacology Tacrolimus TOR protein TOR Serine-Threonine Kinases Workers (insect caste)
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