Uropathogenic Escherichia coli P and Type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction

The progression of a natural bacterial infection is a dynamic process influenced by the physiological characteristics of the target organ. Recent developments in live animal imaging allow for the study of the dynamic microbe-host interplay in real-time as the infection progresses within an organ of...

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Veröffentlicht in:	PLoS pathogens 2011-02, Vol.7 (2), p.e1001298-e1001298
Hauptverfasser:	Melican, Keira, Sandoval, Ruben M, Kader, Abdul, Josefsson, Lina, Tanner, George A, Molitoris, Bruce A, Richter-Dahlfors, Agneta
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria Bacterial Adhesion Bacterial diseases Bacterial infections Biofilms Causes of Colonization E coli Escherichia coli Escherichia coli Infections - microbiology Female Filtrate Filtration Fimbriae Proteins - metabolism Fimbriae, Bacterial - physiology Health aspects Infections Kidney - microbiology Kidney - physiopathology Kidney diseases Microbiology Microbiology/Cellular Microbiology and Pathogenesis Nephrology Nephrons - microbiology Nephrons - physiopathology Physiology Proteins Rats Rats, Sprague-Dawley Ureteral Obstruction - pathology Uropathogenic Escherichia coli - physiology
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