NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases

NleG homologues constitute the largest family of Type 3 effectors delivered by pathogenic E. coli, with fourteen members in the enterohaemorrhagic (EHEC) O157:H7 strain alone. Identified recently as part of the non-LEE-encoded (Nle) effector set, this family remained uncharacterised and shared no se...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS pathogens 2010-06, Vol.6 (6), p.e1000960
Hauptverfasser:	Wu, Bin, Skarina, Tatiana, Yee, Adelinda, Jobin, Marie-Claude, Dileo, Rosa, Semesi, Anthony, Fares, Christophe, Lemak, Alexander, Coombes, Brian K, Arrowsmith, Cheryl H, Singer, Alexander U, Savchenko, Alexei
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacteria Bacteriology Biochemistry E coli Enterohemorrhagic Escherichia coli - enzymology Enterohemorrhagic Escherichia coli - genetics Enterohemorrhagic Escherichia coli - growth & development Enzymes Escherichia coli Escherichia coli Proteins - chemistry Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Genetic aspects Health aspects Humans Infectious Diseases/Bacterial Infections Ligases Medical research Molecular Sequence Data Mutagenesis, Site-Directed Mutation - genetics Nuclear Magnetic Resonance, Biomolecular Physiological aspects Protein Conformation Proteins R&D Research & development RING Finger Domains Sequence Homology, Amino Acid Signal transduction Spectrum analysis Ubiquitin Ubiquitin-Conjugating Enzymes - genetics Ubiquitin-Conjugating Enzymes - metabolism Ubiquitin-Protein Ligases - chemistry Ubiquitin-Protein Ligases - genetics Ubiquitin-Protein Ligases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!